Bone Marrow Adipocytes Contribute to Tumor Microenvironment-Driven Chemoresistance via Sequestration of Doxorubicin

SIMPLE SUMMARY: Despite substantial progress and effort, the clinical efficacy of chemotherapy remains suboptimal due to chemoresistance, which is partly attributed to adipocytes in the tumor microenvironment. Adipocytes, major stromal cells in the bone marrow, are known to uptake lipophilic molecul...

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Detalles Bibliográficos
Autores principales: Kwak, Jun-Goo, Lee, Jungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216070/
https://www.ncbi.nlm.nih.gov/pubmed/37345073
http://dx.doi.org/10.3390/cancers15102737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216070/
https://www.ncbi.nlm.nih.gov/pubmed/37345073
http://dx.doi.org/10.3390/cancers15102737

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