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Bone Marrow Adipocytes Contribute to Tumor Microenvironment-Driven Chemoresistance via Sequestration of Doxorubicin
SIMPLE SUMMARY: Despite substantial progress and effort, the clinical efficacy of chemotherapy remains suboptimal due to chemoresistance, which is partly attributed to adipocytes in the tumor microenvironment. Adipocytes, major stromal cells in the bone marrow, are known to uptake lipophilic molecul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216070/ https://www.ncbi.nlm.nih.gov/pubmed/37345073 http://dx.doi.org/10.3390/cancers15102737 |