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Compromised Myelin and Axonal Molecular Organization Following Adult-Onset Sulfatide Depletion

3-O-sulfogalactosylceramide, or sulfatide, is a prominent myelin glycosphingolipid reduced in the normal appearing white matter (NAWM) in Multiple Sclerosis (MS), indicating that sulfatide reduction precedes demyelination. Using a mouse model that is constitutively depleted of sulfatide, we previous...

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Detalles Bibliográficos
Autores principales: Dustin, Elizabeth, Suarez-Pozos, Edna, Stotesberry, Camryn, Qiu, Shulan, Palavicini, Juan Pablo, Han, Xianlin, Dupree, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216104/
https://www.ncbi.nlm.nih.gov/pubmed/37239102
http://dx.doi.org/10.3390/biomedicines11051431