Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations

Recent progress in CRISPR gene editing tools has substantially increased the opportunities for curing devastating genetic diseases. Here we compare in-frame deletion by CRISPR-based non-homologous blunt end joining (NHBEJ), homology-directed repair (HDR), and prime editing (PE, PE2, and PE3)-based c...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoying, Qu, Kunli, Curci, Benedetta, Yang, Huanming, Bolund, Lars, Lin, Lin, Luo, Yonglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216110/
https://www.ncbi.nlm.nih.gov/pubmed/37238739
http://dx.doi.org/10.3390/biom13050870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216110/
https://www.ncbi.nlm.nih.gov/pubmed/37238739
http://dx.doi.org/10.3390/biom13050870

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