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Non-Expressed Donor KIR3DL1 Alleles May Represent a Risk Factor for Relapse after T-Replete Haploidentical Hematopoietic Stem Cell Transplantation

SIMPLE SUMMARY: Natural killer (NK) cells are key cytotoxic effectors against leukemic cells. The polymorphism of killer cell immunoglobulin-like receptor (KIR) genes plays a crucial role in the NK cell repertoire. In particular, different levels of KIR3DL1 expression on the NK cell surface are desc...

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Detalles Bibliográficos
Autores principales: Legrand, Nolwenn, Salameh, Perla, Jullien, Maxime, Chevallier, Patrice, Ferron, Enora, David, Gaelle, Devilder, Marie-Claire, Willem, Catherine, Gendzekhadze, Ketevan, Parham, Peter, Retière, Christelle, Gagne, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216127/
https://www.ncbi.nlm.nih.gov/pubmed/37345091
http://dx.doi.org/10.3390/cancers15102754