Molecular Mechanisms Driving and Regulating the AAA+ ATPase VCP/p97, an Important Therapeutic Target for Treating Cancer, Neurological and Infectious Diseases

p97/VCP, a highly conserved type II ATPase associated with diverse cellular activities (AAA+ ATPase), is an important therapeutic target in the treatment of neurodegenerative diseases and cancer. p97 performs a variety of functions in the cell and facilitates virus replication. It is a mechanochemic...

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Detalles Bibliográficos
Autores principales: Valimehr, Sepideh, Sethi, Ashish, Shukla, Manjari, Bhattacharyya, Sudipta, Kazemi, Mohsen, Rouiller, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216129/
https://www.ncbi.nlm.nih.gov/pubmed/37238606
http://dx.doi.org/10.3390/biom13050737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216129/
https://www.ncbi.nlm.nih.gov/pubmed/37238606
http://dx.doi.org/10.3390/biom13050737

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