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Molecular Mechanisms Driving and Regulating the AAA+ ATPase VCP/p97, an Important Therapeutic Target for Treating Cancer, Neurological and Infectious Diseases
p97/VCP, a highly conserved type II ATPase associated with diverse cellular activities (AAA+ ATPase), is an important therapeutic target in the treatment of neurodegenerative diseases and cancer. p97 performs a variety of functions in the cell and facilitates virus replication. It is a mechanochemic...
Autores principales: | Valimehr, Sepideh, Sethi, Ashish, Shukla, Manjari, Bhattacharyya, Sudipta, Kazemi, Mohsen, Rouiller, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216129/ https://www.ncbi.nlm.nih.gov/pubmed/37238606 http://dx.doi.org/10.3390/biom13050737 |
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