Inhibition of NADPH Oxidase (NOX) 2 Mitigates Colitis in Mice with Impaired Macrophage AMPK Function

Macrophage adenosine monophosphate-activated protein kinase (AMPK) limits the development of experimental colitis. AMPK activation inhibits NADPH oxidase (NOX) 2 expression, reactive oxygen species (ROS) generation, and pro-inflammatory cytokine secretion in macrophages during inflammation, while in...

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Detalles Bibliográficos
Autores principales: Banskota, Suhrid, Wang, Huaqing, Kwon, Yun Han, Gautam, Jaya, Haq, Sabah, Grondin, Jensine, Steinberg, Gregory R., Khan, Waliul I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216132/
https://www.ncbi.nlm.nih.gov/pubmed/37239114
http://dx.doi.org/10.3390/biomedicines11051443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216132/
https://www.ncbi.nlm.nih.gov/pubmed/37239114
http://dx.doi.org/10.3390/biomedicines11051443

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