Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico by a Spatial Quantitative Systems Pharmacology Model

SIMPLE SUMMARY: We introduced a novel approach to quantitatively validate the performance of a hybrid spatio-temporal method called spatial quantitative systems pharmacology (spQSP). This platform is composed of a compartmental QSP model describing tumor growth dynamics, anti-tumor immune response a...

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Detalles Bibliográficos
Autores principales: Nikfar, Mehdi, Mi, Haoyang, Gong, Chang, Kimko, Holly, Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216176/
https://www.ncbi.nlm.nih.gov/pubmed/37345087
http://dx.doi.org/10.3390/cancers15102750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216176/
https://www.ncbi.nlm.nih.gov/pubmed/37345087
http://dx.doi.org/10.3390/cancers15102750

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