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Uptake-Dependent and -Independent Effects of Fibroblasts-Derived Extracellular Vesicles on Bone Marrow Endothelial Cells from Patients with Multiple Myeloma: Therapeutic and Clinical Implications

Extracellular vesicles (EVs) have emerged as important players in cell-to-cell communication within the bone marrow (BM) of multiple myeloma (MM) patients, where they mediate several tumor-associated processes. Here, we investigate the contribution of fibroblasts-derived EVs (FBEVs) in supporting BM...

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Detalles Bibliográficos
Autores principales: Lamanuzzi, Aurelia, Saltarella, Ilaria, Reale, Antonia, Melaccio, Assunta, Solimando, Antonio Giovanni, Altamura, Concetta, Tamma, Grazia, Storlazzi, Clelia Tiziana, Tolomeo, Doron, Desantis, Vanessa, Mariggiò, Maria Addolorata, Desaphy, Jean-François, Spencer, Andrew, Vacca, Angelo, Apollonio, Benedetta, Frassanito, Maria Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216205/
https://www.ncbi.nlm.nih.gov/pubmed/37239071
http://dx.doi.org/10.3390/biomedicines11051400