Ketamine Reduces the Surface Density of the Astroglial Kir4.1 Channel and Inhibits Voltage-Activated Currents in a Manner Similar to the Action of Ba(2+) on K(+) Currents

A single sub-anesthetic dose of ketamine evokes rapid and long-lasting beneficial effects in patients with a major depressive disorder. However, the mechanisms underlying this effect are unknown. It has been proposed that astrocyte dysregulation of extracellular K(+) concentration ([K(+)](o)) alters...

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Detalles Bibliográficos
Autores principales: Božić, Mićo, Pirnat, Samo, Fink, Katja, Potokar, Maja, Kreft, Marko, Zorec, Robert, Stenovec, Matjaž
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216244/
https://www.ncbi.nlm.nih.gov/pubmed/37408194
http://dx.doi.org/10.3390/cells12101360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216244/
https://www.ncbi.nlm.nih.gov/pubmed/37408194
http://dx.doi.org/10.3390/cells12101360

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