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Glial Glutamate Transporter Modulation Prevents Development of Complete Freund’s Adjuvant-Induced Hyperalgesia and Allodynia in Mice

Glial glutamate transporter (GLT-1) modulation in the hippocampus and anterior cingulate cortex (ACC) is critically involved in nociceptive pain. The objective of the study was to investigate the effects of 3-[[(2-methylphenyl) methyl] thio]-6-(2-pyridinyl)-pyridazine (LDN-212320), a GLT-1 activator...

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Detalles Bibliográficos
Autores principales: Alotaibi, Ghallab, Khan, Amna, Ronan, Patrick J., Lutfy, Kabirullah, Rahman, Shafiqur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216248/
https://www.ncbi.nlm.nih.gov/pubmed/37239279
http://dx.doi.org/10.3390/brainsci13050807