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β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats

Mesolimbic nicotinic acetylcholine receptor (nAChRs) activation is necessary for nicotine reinforcement behavior, but it is unknown whether selective activation of nAChRs in the dopamine (DA) reward pathway is sufficient to support nicotine reinforcement. In this study, we tested the hypothesis that...

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Detalles Bibliográficos
Autores principales: Walker, Noah B., Yan, Yijin, Tapia, Melissa A., Tucker, Brenton R., Thomas, Leanne N., George, Brianna E., West, Alyssa M., Marotta, Christopher B., Lester, Henry A., Dougherty, Dennis A., Holleran, Katherine M., Jones, Sara R., Drenan, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216253/
https://www.ncbi.nlm.nih.gov/pubmed/37193602
http://dx.doi.org/10.1523/ENEURO.0449-22.2023