Cargando…
β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats
Mesolimbic nicotinic acetylcholine receptor (nAChRs) activation is necessary for nicotine reinforcement behavior, but it is unknown whether selective activation of nAChRs in the dopamine (DA) reward pathway is sufficient to support nicotine reinforcement. In this study, we tested the hypothesis that...
Autores principales: | Walker, Noah B., Yan, Yijin, Tapia, Melissa A., Tucker, Brenton R., Thomas, Leanne N., George, Brianna E., West, Alyssa M., Marotta, Christopher B., Lester, Henry A., Dougherty, Dennis A., Holleran, Katherine M., Jones, Sara R., Drenan, Ryan M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216253/ https://www.ncbi.nlm.nih.gov/pubmed/37193602 http://dx.doi.org/10.1523/ENEURO.0449-22.2023 |
Ejemplares similares
-
Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability
por: Henderson, Brandon J, et al.
Publicado: (2017) -
Differential Nicotinic Modulation of Glutamatergic and GABAergic VTA Microcircuits
por: Yan, Yijin, et al.
Publicado: (2019) -
Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain
por: Peng, Can, et al.
Publicado: (2017) -
Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior
por: Akers, Austin T., et al.
Publicado: (2020) -
Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine
por: Morozova, Ekaterina, et al.
Publicado: (2020)