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Introduction of a Polyethylene Glycol Linker Improves Uptake of (67)Cu-NOTA-Conjugated Lactam-Cyclized Alpha-Melanocyte-Stimulating Hormone Peptide in Melanoma

SIMPLE SUMMARY: There is a need to develop new theranostic approaches for malignant melanoma. Only 35% of patients with metastatic melanoma reach the milestone of 5-year survival, despite the success of new immunotherapy. We have developed a new class of peptides to target melanocortin-1 receptors (...

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Detalles Bibliográficos
Autores principales: Qiao, Zheng, Xu, Jingli, Fisher, Darrell R., Gonzalez, Rene, Miao, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216305/
https://www.ncbi.nlm.nih.gov/pubmed/37345092
http://dx.doi.org/10.3390/cancers15102755