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Co-Stimulation of AGEs and LPS Induces Inflammatory Mediators through PLCγ1/JNK/NF-κB Pathway in MC3T3-E1 Cells

Advanced glycation end-products (AGEs) are increased under hyperglycemia in vivo and are associated with the onset of diabetes. According to previous studies, AGEs exacerbate inflammatory diseases. However, the mechanism by which AGEs aggravate osteoblast inflammation remains unknown. Therefore, the...

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Detalles Bibliográficos
Autores principales: Tanabe, Natsuko, Tomita, Keiko, Manaka, Soichiro, Ichikawa, Risa, Takayama, Tadahiro, Kawato, Takayuki, Ono, Misae, Masai, Yuma, Utsu, Akihisa, Suzuki, Naoto, Sato, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216316/
https://www.ncbi.nlm.nih.gov/pubmed/37408216
http://dx.doi.org/10.3390/cells12101383