Cholecystokinin Receptor Antagonist Induces Pancreatic Stellate Cell Plasticity Rendering the Tumor Microenvironment Less Oncogenic

SIMPLE SUMMARY: The tumor microenvironment of pancreatic cancer consists of dense fibrotic stroma, which, to a certain extent, accounts for the relative drug resistance of this malignancy. Activated pancreatic stellate cells (PSC) and myofibroblasts are responsible for this fibrosis, and strategies...

Descripción completa

Detalles Bibliográficos
Autores principales: Jolly, Gurbani, Duka, Tetyana, Shivapurkar, Narayan, Chen, Wenqiang, Bansal, Sunil, Cheema, Amrita, Smith, Jill P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216345/
https://www.ncbi.nlm.nih.gov/pubmed/37345148
http://dx.doi.org/10.3390/cancers15102811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216345/
https://www.ncbi.nlm.nih.gov/pubmed/37345148
http://dx.doi.org/10.3390/cancers15102811

Ejemplares similares