Glabridin Therapy Reduces Chronic Allodynia, Spinal Microgliosis, and Dendritic Spine Generation by Inhibiting Fractalkine-CX3CR1 Signaling in a Mouse Model of Tibial Fractures

Patients undergoing bone fractures frequently suffer from irritating chronic pain after orthopedic repairs. Chemokine-mediated interactions between neurons and microglia are important steps for neuroinflammation and excitatory synaptic plasticity during the spinal transmission of pathological pain....

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Detalles Bibliográficos
Autores principales: Long, Juan, Liu, Hongbing, Qiu, Zhimin, Xiao, Zhong, Lu, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216346/
https://www.ncbi.nlm.nih.gov/pubmed/37239211
http://dx.doi.org/10.3390/brainsci13050739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216346/
https://www.ncbi.nlm.nih.gov/pubmed/37239211
http://dx.doi.org/10.3390/brainsci13050739

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