Structural Insight into the Mechanism of σ32-Mediated Transcription Initiation of Bacterial RNA Polymerase

Bacterial RNA polymerases (RNAP) form distinct holoenzymes with different σ factors to initiate diverse gene expression programs. In this study, we report a cryo-EM structure at 2.49 Å of RNA polymerase transcription complex containing a temperature-sensitive bacterial σ factor, σ(32) (σ(32)-RPo). T...

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Detalles Bibliográficos
Autores principales: Lu, Qiang, Chen, Taiyu, Wang, Jiening, Wang, Feng, Ye, Wenlong, Ma, Lixin, Wu, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216364/
https://www.ncbi.nlm.nih.gov/pubmed/37238608
http://dx.doi.org/10.3390/biom13050738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216364/
https://www.ncbi.nlm.nih.gov/pubmed/37238608
http://dx.doi.org/10.3390/biom13050738

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