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Structural Insight into the Mechanism of σ32-Mediated Transcription Initiation of Bacterial RNA Polymerase

Bacterial RNA polymerases (RNAP) form distinct holoenzymes with different σ factors to initiate diverse gene expression programs. In this study, we report a cryo-EM structure at 2.49 Å of RNA polymerase transcription complex containing a temperature-sensitive bacterial σ factor, σ(32) (σ(32)-RPo). T...

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Detalles Bibliográficos
Autores principales:	Lu, Qiang, Chen, Taiyu, Wang, Jiening, Wang, Feng, Ye, Wenlong, Ma, Lixin, Wu, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216364/ https://www.ncbi.nlm.nih.gov/pubmed/37238608 http://dx.doi.org/10.3390/biom13050738

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