STING-Triggered CNS Inflammation in Human Neurodegenerative Diseases

Background: Some neurodegenerative diseases have an element of neuroinflammation that is triggered by viral nucleic acids, resulting in the generation of type I interferons. In the cGAS-STING pathway, microbial and host-derived DNA bind and activate the DNA sensor cGAS, and the resulting cyclic dinu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferecskó, Alex S., Smallwood, Miranda J., Moore, Adrian, Liddle, Corin, Newcombe, Jia, Holley, Janet, Whatmore, Jacqueline, Gutowski, Nicholas J., Eggleton, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216406/
https://www.ncbi.nlm.nih.gov/pubmed/37239045
http://dx.doi.org/10.3390/biomedicines11051375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216406/
https://www.ncbi.nlm.nih.gov/pubmed/37239045
http://dx.doi.org/10.3390/biomedicines11051375

Ejemplares similares