Lipoxin A4 (LXA4) Reduces Alkali-Induced Corneal Inflammation and Neovascularization and Upregulates a Repair Transcriptome

Purpose: To investigate the anti-inflammatory and anti-angiogenic effects of the bioactive lipid mediator LXA4 on a rat model of severe corneal alkali injury. Methods: To induce a corneal alkali injury in the right eyes of anesthetized Sprague Dawley rats. They were injured with a Φ 4 mm filter pape...

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Detalles Bibliográficos
Autores principales: He, Jiucheng, Pham, Thang L., Kakazu, Azucena H., Ponnath, Abhilash, Do, Khanh V., Bazan, Haydee E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216426/
https://www.ncbi.nlm.nih.gov/pubmed/37238701
http://dx.doi.org/10.3390/biom13050831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216426/
https://www.ncbi.nlm.nih.gov/pubmed/37238701
http://dx.doi.org/10.3390/biom13050831

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