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Angiogenesis in the Outer Membrane of Chronic Subdural Hematomas through Thrombin-Cleaved Osteopontin and the Integrin α9 and Integrin β1 Signaling Pathways

Background: A chronic subdural hematoma (CSDH) is considered to be an inflammatory and angiogenic disease. The CSDH outer membrane, which contains inflammatory cells, plays an important role in CSDH development. Osteopontin (OPN) is an extracellular matrix protein that is cleaved by thrombin, genera...

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Detalles Bibliográficos
Autores principales: Osuka, Koji, Ohmichi, Yusuke, Ohmichi, Mika, Honma, Satoru, Suzuki, Chiharu, Aoyama, Masahiro, Iwami, Kenichiro, Watanabe, Yasuo, Miyachi, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216439/
https://www.ncbi.nlm.nih.gov/pubmed/37239111
http://dx.doi.org/10.3390/biomedicines11051440