Signaling Switching from Hedgehog-GLI to MAPK Signaling Potentially Serves as a Compensatory Mechanism in Melanoma Cell Lines Resistant to GANT-61

Background: Melanoma represents the deadliest skin cancer due to its cell plasticity which results in high metastatic potential and chemoresistance. Melanomas frequently develop resistance to targeted therapy; therefore, new combination therapy strategies are required. Non-canonical signaling intera...

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Detalles Bibliográficos
Autores principales: Piteša, Nikolina, Kurtović, Matea, Bartoniček, Nenad, Gkotsi, Danai S., Čonkaš, Josipa, Petrić, Tina, Musani, Vesna, Ozretić, Petar, Riobo-Del Galdo, Natalia A., Sabol, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216463/
https://www.ncbi.nlm.nih.gov/pubmed/37239024
http://dx.doi.org/10.3390/biomedicines11051353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216463/
https://www.ncbi.nlm.nih.gov/pubmed/37239024
http://dx.doi.org/10.3390/biomedicines11051353

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