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Nicotine Administration Augments Abdominal Aortic Aneurysm Progression in Rats

Inflammation and elastin degradation are key hallmarks in the pathogenesis of abdominal aortic aneurysms (AAAs). It has been acknowledged that activation of alpha7 nicotinic acetylcholine receptors (α7nAChRs) attenuates inflammation, termed the cholinergic anti-inflammatory pathway (CAP). Thus, we h...

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Detalles Bibliográficos
Autores principales: Hadzikadunic, Hana, Sjælland, Tea Bøvling, Lindholt, Jes S., Steffensen, Lasse Bach, Beck, Hans Christian, Kavaliunaite, Egle, Rasmussen, Lars Melholt, Stubbe, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216524/
https://www.ncbi.nlm.nih.gov/pubmed/37239088
http://dx.doi.org/10.3390/biomedicines11051417