Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G

Cathepsin G (CatG) is a pro-inflammatory neutrophil serine protease that is important for host defense, and has been implicated in several inflammatory disorders. Hence, inhibition of CatG holds much therapeutic potential; however, only a few inhibitors have been identified to date, and none have re...

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Detalles Bibliográficos
Autores principales: Afosah, Daniel K., Fayyad, Rawan M., Puliafico, Valerie R., Merrell, Spencer, Langmia, Eltice K., Diagne, Sophie R., Al-Horani, Rami A., Desai, Umesh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216581/
https://www.ncbi.nlm.nih.gov/pubmed/37238630
http://dx.doi.org/10.3390/biom13050760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216581/
https://www.ncbi.nlm.nih.gov/pubmed/37238630
http://dx.doi.org/10.3390/biom13050760

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