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Homogeneous, Synthetic, Non-Saccharide Glycosaminoglycan Mimetics as Potent Inhibitors of Human Cathepsin G
Cathepsin G (CatG) is a pro-inflammatory neutrophil serine protease that is important for host defense, and has been implicated in several inflammatory disorders. Hence, inhibition of CatG holds much therapeutic potential; however, only a few inhibitors have been identified to date, and none have re...
Autores principales: | Afosah, Daniel K., Fayyad, Rawan M., Puliafico, Valerie R., Merrell, Spencer, Langmia, Eltice K., Diagne, Sophie R., Al-Horani, Rami A., Desai, Umesh R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216581/ https://www.ncbi.nlm.nih.gov/pubmed/37238630 http://dx.doi.org/10.3390/biom13050760 |
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