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Decreased MARCKS Protein Expression in Kidney Cortex Membrane Fractions of Cathepsin B Knockout Mice Is Associated with Reduced Lysophosphatidylcholine and Protein Kinase C Activity

Cathpesin B is a multi-functional protease that plays numerous roles in physiology and pathophysiology. We hypothesized that actin cytoskeleton proteins that are substrates of cathepsin B, various lipids, and kinases that are regulated by lipids would be down-regulated in the kidney of cathepsin B k...

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Detalles Bibliográficos
Autores principales: Kawakibi, Tamim, Bala, Niharika, Liu, Lauren P., Searcy, Louis A., Denslow, Nancy D., Alli, Abdel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216610/
https://www.ncbi.nlm.nih.gov/pubmed/37239160
http://dx.doi.org/10.3390/biomedicines11051489