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CVAM: CNA Profile Inference of the Spatial Transcriptome Based on the VGAE and HMM

Tumors are often polyclonal due to copy number alteration (CNA) events. Through the CNA profile, we can understand the tumor heterogeneity and consistency. CNA information is usually obtained through DNA sequencing. However, many existing studies have shown a positive correlation between the gene ex...

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Detalles Bibliográficos
Autores principales: Ma, Jian, Guo, Jingjing, Fan, Zhiwei, Zhao, Weiling, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216626/
https://www.ncbi.nlm.nih.gov/pubmed/37238637
http://dx.doi.org/10.3390/biom13050767