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Trimethylamine N-Oxide Exacerbates Neuroinflammation and Motor Dysfunction in an Acute MPTP Mice Model of Parkinson’s Disease

Observational studies have shown abnormal changes in trimethylamine N-oxide (TMAO) levels in the peripheral circulatory system of Parkinson’s disease (PD) patients. TMAO is a gut microbiota metabolite that can cross the blood–brain barrier and is strongly related to neuroinflammation. Neuroinflammat...

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Detalles Bibliográficos
Autores principales: Quan, Wei, Qiao, Chen-Meng, Niu, Gu-Yu, Wu, Jian, Zhao, Li-Ping, Cui, Chun, Zhao, Wei-Jiang, Shen, Yan-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216692/
https://www.ncbi.nlm.nih.gov/pubmed/37239262
http://dx.doi.org/10.3390/brainsci13050790