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Dimethyl Fumarate as Potential Treatment for Alzheimer’s Disease: Rationale and Clinical Trial Design

Alzheimer’s Disease (AD) is a debilitating disease that leads to severe cognitive impairment and functional decline. The role of tau hyperphosphorylation and amyloid plaque deposition in the pathophysiology of AD has been well described; however, neuroinflammation and oxidative stress related to sus...

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Detalles Bibliográficos
Autores principales: Sharkus, Robert, Thakkar, Richa, Kolson, Dennis L., Constantinescu, Cris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216730/
https://www.ncbi.nlm.nih.gov/pubmed/37239057
http://dx.doi.org/10.3390/biomedicines11051387