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Fluid shear stress regulates the survival of circulating tumor cells via nuclear expansion

Distant metastasis mainly occurs through hematogenous dissemination, where suspended circulating tumor cells (CTCs) experience a considerable level of fluid shear stress. We recently reported that shear flow induced substantial apoptosis of CTCs, although a small subpopulation could still persist. H...

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Detalles Bibliográficos
Autores principales: Xu, Zichen, Li, Keming, Xin, Ying, Tang, Kai, Yang, Mo, Wang, Guixue, Tan, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216746/
https://www.ncbi.nlm.nih.gov/pubmed/35510498
http://dx.doi.org/10.1242/jcs.259586