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Galectin-3 and Epithelial MUC1 Mucin—Interactions Supporting Cancer Development

SIMPLE SUMMARY: MUC1 mucin with T antigen and galectin-3 with high affinity to T disaccharide are both overexpressed in a variety of human cancers. Their mutual interactions support cancer development, attenuate anoikis, promote cancer cells proliferation, invasiveness and metastasis. The inhibition...

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Detalles Bibliográficos
Autor principal: Radziejewska, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216753/
https://www.ncbi.nlm.nih.gov/pubmed/37345016
http://dx.doi.org/10.3390/cancers15102680