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New Flow Cytometric Methods for Monitoring STAT5 Signaling Reveal Responses to SARS-CoV-2 Antigen-Specific Stimulation in FOXP3+ Regulatory T Cells also in Patients with Advanced Chronic Lymphocytic Leukemia

Increased frequency of CD4(+)CD25(+) regulatory T-cells (Treg) has been associated with disease progression in chronic lymphocytic leukemia (CLL). Flow cytometric methods, which allow for the simultaneous analysis of their specific transcription factor Foxp3 and activated STAT proteins, together wit...

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Detalles Bibliográficos
Autores principales: Roškar, Zlatko, Dreisinger, Mojca, Tič, Primož, Homšak, Evgenija, Bevc, Sebastjan, Goropevšek, Aleš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216754/
https://www.ncbi.nlm.nih.gov/pubmed/37232900
http://dx.doi.org/10.3390/bios13050539