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Regulation of IDO2 by the Aryl Hydrocarbon Receptor (AhR) in Breast Cancer

Indoleamine 2,3-dioxygenase 2 (IDO2) is a tryptophan-catabolizing enzyme and a homolog of IDO1 with a distinct expression pattern compared with IDO1. In dendritic cells (DCs), IDO activity and the resulting changes in tryptophan level regulate T-cell differentiation and promote immune tolerance. Rec...

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Detalles Bibliográficos
Autores principales: Kado, Sarah Y., Bein, Keith, Castaneda, Alejandro R., Pouraryan, Arshia A., Garrity, Nicole, Ishihara, Yasuhiro, Rossi, Andrea, Haarmann-Stemmann, Thomas, Sweeney, Colleen A., Vogel, Christoph F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216785/
https://www.ncbi.nlm.nih.gov/pubmed/37408267
http://dx.doi.org/10.3390/cells12101433