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The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia

Neuroinflammation is a unifying factor among all acute central nervous system (CNS) injuries and chronic neurodegenerative disorders. Here, we used immortalized microglial (IMG) cells and primary microglia (PMg) to understand the roles of the GTPase Ras homolog gene family member A (RhoA) and its do...

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Detalles Bibliográficos
Autores principales: Glotfelty, Elliot J., Tovar-y-Romo, Luis B., Hsueh, Shih-Chang, Tweedie, David, Li, Yazhou, Harvey, Brandon K., Hoffer, Barry J., Karlsson, Tobias E., Olson, Lars, Greig, Nigel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216802/
https://www.ncbi.nlm.nih.gov/pubmed/37408199
http://dx.doi.org/10.3390/cells12101367