Genetic Ablation of the MET Oncogene Defines a Crucial Role of the HGF/MET Axis in Cell-Autonomous Functions Driving Tumor Dissemination

SIMPLE SUMMARY: The MET receptor and its ligand Hepatocyte Growth Factor (HGF) sustain cell proliferation, survival, motility, and invasion. Several pieces of evidence suggest that these biological activities support the metastatic potential of transformed cells. Cancer cell dissemination is sustain...

Descripción completa

Detalles Bibliográficos
Autores principales: Modica, Chiara, Cortese, Marco, Bersani, Francesca, Lombardi, Andrea Maria, Napoli, Francesca, Righi, Luisella, Taulli, Riccardo, Basilico, Cristina, Vigna, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216813/
https://www.ncbi.nlm.nih.gov/pubmed/37345079
http://dx.doi.org/10.3390/cancers15102742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216813/
https://www.ncbi.nlm.nih.gov/pubmed/37345079
http://dx.doi.org/10.3390/cancers15102742

Ejemplares similares