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Genetic Ablation of the MET Oncogene Defines a Crucial Role of the HGF/MET Axis in Cell-Autonomous Functions Driving Tumor Dissemination
SIMPLE SUMMARY: The MET receptor and its ligand Hepatocyte Growth Factor (HGF) sustain cell proliferation, survival, motility, and invasion. Several pieces of evidence suggest that these biological activities support the metastatic potential of transformed cells. Cancer cell dissemination is sustain...
Autores principales: | Modica, Chiara, Cortese, Marco, Bersani, Francesca, Lombardi, Andrea Maria, Napoli, Francesca, Righi, Luisella, Taulli, Riccardo, Basilico, Cristina, Vigna, Elisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216813/ https://www.ncbi.nlm.nih.gov/pubmed/37345079 http://dx.doi.org/10.3390/cancers15102742 |
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