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Synthesis and Characterization of PCL-Idebenone Nanoparticles for Potential Nose-to-Brain Delivery

The present work is focused on the preparation of an optimal model of poly-ε-caprolactone nanoparticles as potential carriers for nasal administration of idebenone. A solvent/evaporation technique was used for nanoparticle preparation. Poly-ε-caprolactone with different molecular weights (14,000 and...

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Detalles Bibliográficos
Autores principales: Boyuklieva, Radka, Hristozova, Asya, Pilicheva, Bissera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216815/
https://www.ncbi.nlm.nih.gov/pubmed/37239161
http://dx.doi.org/10.3390/biomedicines11051491