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Pathophysiological Role of Microglial Activation Induced by Blood-Borne Proteins in Alzheimer’s Disease

The blood–brain barrier (BBB) restricts entry of neurotoxic plasma components, blood cells, and pathogens into the brain, leading to proper neuronal functioning. BBB impairment leads to blood-borne protein infiltration such as prothrombin, thrombin, prothrombin kringle-2, fibrinogen, fibrin, and oth...

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Detalles Bibliográficos
Autores principales: Kim, Sehwan, Sharma, Chanchal, Jung, Un Ju, Kim, Sang Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216844/
https://www.ncbi.nlm.nih.gov/pubmed/37239054
http://dx.doi.org/10.3390/biomedicines11051383