Potential of Synthetic and Natural Compounds as Novel Histone Deacetylase Inhibitors for the Treatment of Hematological Malignancies

SIMPLE SUMMARY: Histone deacetylases (HDACs) are epigenetic regulators that influence chromatin structure and gene transcription, but also the function of non-histone targets like chaperones and proteins participating in the DNA damage response. Histone modifications are implicated in cancer and HDA...

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Detalles Bibliográficos
Autores principales: Pal, Dilipkumar, Raj, Khushboo, Nandi, Shyam Sundar, Sinha, Surajit, Mishra, Abhishek, Mondal, Arijit, Lagoa, Ricardo, Burcher, Jack T., Bishayee, Anupam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216849/
https://www.ncbi.nlm.nih.gov/pubmed/37345145
http://dx.doi.org/10.3390/cancers15102808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216849/
https://www.ncbi.nlm.nih.gov/pubmed/37345145
http://dx.doi.org/10.3390/cancers15102808

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