Basket to Purkinje Cell Inhibitory Ephaptic Coupling Is Abolished in Episodic Ataxia Type 1

Dominantly inherited missense mutations of the KCNA1 gene, which encodes the K(V)1.1 potassium channel subunit, cause Episodic Ataxia type 1 (EA1). Although the cerebellar incoordination is thought to arise from abnormal Purkinje cell output, the underlying functional deficit remains unclear. Here w...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Henry G. S., Kullmann, Dimitri M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216961/
https://www.ncbi.nlm.nih.gov/pubmed/37408217
http://dx.doi.org/10.3390/cells12101382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216961/
https://www.ncbi.nlm.nih.gov/pubmed/37408217
http://dx.doi.org/10.3390/cells12101382

Ejemplares similares