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Basket to Purkinje Cell Inhibitory Ephaptic Coupling Is Abolished in Episodic Ataxia Type 1

Dominantly inherited missense mutations of the KCNA1 gene, which encodes the K(V)1.1 potassium channel subunit, cause Episodic Ataxia type 1 (EA1). Although the cerebellar incoordination is thought to arise from abnormal Purkinje cell output, the underlying functional deficit remains unclear. Here w...

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Detalles Bibliográficos
Autores principales:	Martin, Henry G. S., Kullmann, Dimitri M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10216961/ https://www.ncbi.nlm.nih.gov/pubmed/37408217 http://dx.doi.org/10.3390/cells12101382

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