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Fibroblast Activation Protein-Targeting Minibody-IRDye700DX for Ablation of the Cancer-Associated Fibroblast with Photodynamic Therapy

Fibroblast activation protein (FAP), expressed on cancer-associated fibroblasts, is a target for diagnosis and therapy in multiple tumour types. Strategies to systemically deplete FAP-expressing cells show efficacy; however, these induce toxicities, as FAP-expressing cells are found in normal tissue...

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Detalles Bibliográficos
Autores principales: Smeets, Esther M. M., Dorst, Daphne N., Franssen, Gerben M., van Essen, Merijn S., Frielink, Cathelijne, Stommel, Martijn W. J., Trajkovic-Arsic, Marija, Cheung, Phyllis F., Siveke, Jens T., Wilson, Ian, Mascioni, Alessandro, Aarntzen, Erik H. J. G., van Lith, Sanne A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217124/
https://www.ncbi.nlm.nih.gov/pubmed/37408254
http://dx.doi.org/10.3390/cells12101420