PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction

Aging and obesity are the two prominent driving forces of metabolic dysfunction, yet the common underlying mechanisms remain elusive. PPARγ, a central metabolic regulator and primary drug target combatting insulin resistance, is hyperacetylated in both aging and obesity. By employing a unique adipoc...

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Detalles Bibliográficos
Autores principales: He, Ying, Zhang, Ruotong, Yu, Lexiang, Zahr, Tarik, Li, Xueming, Kim, Tae-Wan, Qiang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217233/
https://www.ncbi.nlm.nih.gov/pubmed/37408258
http://dx.doi.org/10.3390/cells12101424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217233/
https://www.ncbi.nlm.nih.gov/pubmed/37408258
http://dx.doi.org/10.3390/cells12101424

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