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Double Positive CD4(+)CD8(+) (DP) T-Cells Display Distinct Exhaustion Phenotype in Chronic Hepatitis C

In chronic hepatitis C (CHC), characterized by exhaustion of T-cell function, increased frequencies of double-positive (DP) (CD4(+)CD8(+)) cells are present in peripheral blood. We compared the exhaustion phenotype between DP and single positive (SP) T-cells, including HCV-specific cells, and assess...

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Detalles Bibliográficos
Autores principales: Kochanowicz, Anna Maria, Osuch, Sylwia, Berak, Hanna, Kumorek, Aleksandra, Caraballo Cortés, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217244/
https://www.ncbi.nlm.nih.gov/pubmed/37408280
http://dx.doi.org/10.3390/cells12101446