Numerical Optimization of Prednisolone–Tacrolimus Loaded Ultraflexible Transethosomes for Transdermal Delivery Enhancement; Box–Behnken Design, Evaluation, Optimization, and Pharmacokinetic Study

The aim of the present study is to formulate highly permeable carriers (i.e., transethosomes) for enhancing the delivery of prednisolone combined with tacrolimus for both topical and systemic pathological conditions. A Box–Behnken experimental design was implemented in this research. Three independe...

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Detalles Bibliográficos
Autores principales: Alfadhel, Munerah M., Zaki, Randa Mohammed, Aldosari, Basmah Nasser, Sayed, Ossama M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217343/
https://www.ncbi.nlm.nih.gov/pubmed/37232992
http://dx.doi.org/10.3390/gels9050400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217343/
https://www.ncbi.nlm.nih.gov/pubmed/37232992
http://dx.doi.org/10.3390/gels9050400

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