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SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation

Cardiac fibrosis plays an essential role in the development of diastolic dysfunction and contributes to heart failure with preserved ejection fraction (HFpEF). Our previous studies suggested Sirtuin 3 (SIRT3) as a potential target for cardiac fibrosis and heart failure. In the present study, we expl...

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Detalles Bibliográficos
Autores principales: Su, Han, Cantrell, Aubrey C., Chen, Jian-Xiong, Gu, Wei, Zeng, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217433/
https://www.ncbi.nlm.nih.gov/pubmed/37408261
http://dx.doi.org/10.3390/cells12101428