Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain

Activation of intravesical protease activated receptors-4 (PAR4) results in bladder pain through the release of urothelial macrophage migration inhibitory factor (MIF) and high mobility group box-1 (HMGB1). We aimed to identify HMGB1 downstream signaling events at the bladder that mediate HMGB1-indu...

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Detalles Bibliográficos
Autores principales: Ye, Shaojing, Mahmood, Dlovan F. D., Ma, Fei, Leng, Lin, Bucala, Richard, Vera, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217556/
https://www.ncbi.nlm.nih.gov/pubmed/37408274
http://dx.doi.org/10.3390/cells12101440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217556/
https://www.ncbi.nlm.nih.gov/pubmed/37408274
http://dx.doi.org/10.3390/cells12101440

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