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Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain
Activation of intravesical protease activated receptors-4 (PAR4) results in bladder pain through the release of urothelial macrophage migration inhibitory factor (MIF) and high mobility group box-1 (HMGB1). We aimed to identify HMGB1 downstream signaling events at the bladder that mediate HMGB1-indu...
Autores principales: | Ye, Shaojing, Mahmood, Dlovan F. D., Ma, Fei, Leng, Lin, Bucala, Richard, Vera, Pedro L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10217556/ https://www.ncbi.nlm.nih.gov/pubmed/37408274 http://dx.doi.org/10.3390/cells12101440 |
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